Consequently, when a patient shows elevated levels of blood eosinophils, experiences a greater frequency of severe exacerbations in the past year, has developed asthma in adulthood, displays nasal polyps, and continues to rely on oral corticosteroids during the initial evaluation, it indicates a likely favorable outcome from anti-IL5 or anti-IL5Rα treatment options (see Table 1) (3, 45, 47). The gene discussed is IL5; the disease is asthma.