Similarly, Perrin et al. observed elevated levels of IL-2, CCL-5, and interferon-γ along with increased MHC-I expression, in a mouse model of multiple myeloma treated with 213Bi-labelled anti-SDC1 antibody 215, and Malamas et al. demonstrated that in vitro exposure of prostate, lung, and breast cancer cells to 223Ra dichloride resulted in the surface exposure of DAMPs and MHC-I, rendering tumour cells more susceptible to T cell-mediated lysis 213. This evidence concerns the gene SDC1 and neoplasm.