However, our investigation utilizing Hdc-GFP mice revealed that CD11b+Gr-1+ myeloid cells are the predominant HDC-expressing cells in inflammatory-related tumorigenesis 17, myocardial infarction 30, and lower limb ischemia 18, potentially functioning as progenitors for mature neutrophils and monocytes. This evidence concerns the gene ITGAM and myocardial infarction.