Together, in this paper, we identified miR-30a-5p as the only DEMi associated with iron death in HCC using multiple specialized databases such as GSE69164, GSE77509, TCGA and other screening; relevant target lncRNAs were obtained from Inbase and starBase databases; on this basis, survival analysis was performed, and it was finally determined that HCG18 or RRM2 high-expression HCC patients had a poorer prognosis, and miR-30a-5p high-expression HCC patients had a longer survival, linking HCC to ferroptosis. This evidence concerns the gene HCG18 and hepatocellular carcinoma.