Similarly, Cemeroglu et al. [15] reported that the basal insulin requirement was much lower than the bolus requirement compared to adults with T1D, and the highest basal insulin requirement was 40%–45% of the total daily dose at the onset of puberty and the lowest 34% of the total daily dose in the first 7 years of life. The gene discussed is INS; the disease is type 1 diabetes mellitus.