Pediatric T1D guidelines (International Society for Pediatric and Adolescent Diabetes, American Diabetes Association, and Diabetes Canada) recommend screening for DKD with (1) blood pressure measurements at each routine clinic visit and (2) commencement of screening for albuminuria with an annual spot urine albumin-to-creatinine ratio (ACR) at puberty (or 10–12 years of age) and 2–5 years duration of T1D [9–11]. The gene discussed is ALB; the disease is type 1 diabetes mellitus.