Anomalies in the WT1 gene encompass a wide range of diseases, including Beckwith-Wiedemann syndrome, linked to epigenetic anomalies of the 11p15 region; WAGR syndrome (WT, aniridia, genitourinary anomalies, and mental retardation), linked to the deletion of the 11p region; and DDS and Frasier syndrome, linked to pathogenic variants of the WT1 gene. Here, WT1 is linked to Denys-Drash syndrome.