IFITM1 and infection: In female mice, there were 430 DEGs in the infection group (FT) compared with the control group (FC), 195 genes with upregulated expression, such as Ifitm1, Wfdc21, Wfdc17, RARα, and Mgam (P  < 0.001), and 235 genes with downregulated expression, such as Xpo7 and Hmbs (P  < 0.001) (Figure 1(a)).