PRKACB and non-small cell lung carcinoma: In a study aiming to evaluate the expression pattern of PRKACB in NSCLC, Chen et al. found that PRKACB is downregulated in NSCLC tissues, and the upregulation of this gene decreased the number of proliferative, colony-forming cells and invasive cells, indicating that an upregulated PRKACB level may be an effective way to prevent the progression of NSCLC (Chen et al., 2013).