SLC16A1 and head and neck squamous cell carcinoma: In addition, through the construction of stable SLC16A1 knockdown and overexpression models in HNSCC cells along with in vitro and in vivo experiments, the study comprehensively illuminated the pivotal role of SLC16A1 in promoting the proliferation, migration, and invasiveness of HNSCC cells, as well as enhancing their resistance to ferroptosis.