We also found through GSEA analysis of the 33-lncRNA-CESC model are mainly involved in FGFR3 mutant receptor activation, EGFR signaling in GRB2 events, FGFR3 point mutant signaling in cancer, FRS-mediated FGFR1 signaling, EGFR signaling in cancer, downstream signaling in activating FGFR1, and MAP2K and MAPK activation, FGFR1 signaling, Oncogenic MAPK signaling and other signaling pathways. This evidence concerns the gene GRB2 and cancer.