Consistently, we observed significant interactions of fish oil use with variants at GLUT4 (rs5435 in women and rs8082645 in men) on T2D risk (P interaction = 0.030 for rs5435 and 0.047 for rs8082645) among people with prediabetes (Table S11), reinforcing GLUT4 activation as the potential target of n-3 PUFA supplementation in T2D prevention. The gene discussed is SLC2A4; the disease is type 2 diabetes mellitus.