Eleven individuals (median age: 35.2, range: 2.9; 67.2 years) were found to harbour p.Cys1400Ter with c.489+3A>G in cis, had no variant on the other allele on CFTR sequencing and had not displayed any suspect clinical manifestations for CF up to the end of the study period. Here, CFTR is linked to cystic fibrosis.