HLA-DRB1 and myeloid sarcoma: Therefore, we postulated that C. tetani, which had left adaptive genetic signatures on HLA-DRB1*08:03, and B. pertussis, which had left adaptive genetic signatures on HLA-DQB1*03:01 (Figure 2A), may have a significant impact on the genetic susceptibility to MS in the Han Chinese population in the recent evolutionary history.