Yet, the composition of the colonic immune compartment remained durably changed upon infection since infected mice showed a significant increase in the proportion of macrophages (F4/80+, CD11b+, Ly6C/G-), conventional CD4+ T cells (Foxp3-) and both TCRαβ+ CD8+ and TCRγδ+ CD8+ T cells (Fig 2A). This evidence concerns the gene CD8A and infection.