IL17A and pertussis: In KEGG pathway analysis, the up-regulated genes are enriched in cytokine-cytokine receptor interaction, IL-17 signaling pathway, viral protein interaction with cytokine and cytokine receptor, and PI3K-Act signaling pathway, and down-regulated genes are concentrated in the staphylococcus aureus infection, pertussis, complement and coagulation cascades, and NF-kappa B signaling pathway (Figs 6A and B).