The results demonstrated that KLF4 expression is significantly associated with clinical stage in six of the examined cancer types: BRCA (p = 0.0384), KIRC (p = 2.68e − 07), KIRP (p = 1.02e − 06), PAAD (p = 0.0126), TGCT (p = 0.0224), and THCA (p = 0.0393) (Fig S1 in S1 File). Here, KLF4 is linked to cancer.