KLF4 and pancreatic adenocarcinoma: Furthermore, the results of the CPTAC dataset showed lower KLF4 total protein expression in the primary tissues of HNSC and LAUD (Fig S2 in S1 File, p < 0.05) relative to the normal controls, while higher KLF4 expression was noted in PAAD primary tissues (p < 0.05) relative to the normal controls.