Additionally, KLF4 expression and cancer-associated fibroblast infiltration was found to be positively correlated in BRCA, BRCA-LumA, LIHC, and PCPG, while negatively correlated with HNSC, HNSC-HPV-, STAD and TGCT, based on all or most algorithms (Fig 4A). The gene discussed is KLF4; the disease is cancer.