Another meta-analysis of four studies examining the role of CCR7 expression in OS in patients with esophageal squamous cell carcinomas revealed that high CCR7 expression was correlated with a poorer prognosis (HR 2.06, 95% CI 1.56–2.71, p < 0.001) [38]. The gene discussed is CCR7; the disease is esophageal squamous cell carcinoma.