HIF1A and Cerebral ischemia: We explain this effect from the perspective of its impact on the GSH-dependent pathways of endogenous neuroprotection and the increased expression of mRNA for HSP70, HIF-1α, and HIF-3α under conditions of acute experimental cerebral ischemia, as well as the enhancement of glutathione synthesis [80,81,82,83,84,85,86,87,88,89,90].