Within tumor, blood-matched TCR phenotypes were predominantly not proliferating, but were instead consistently cytotoxic (GZMB+ and GZMK+ for CD4+, also GZMK+ and MAIT for CD8+), and also included noncytotoxic CXCL13+ CD4+ and Tregs as observed above (Figure 3D). This evidence concerns the gene GZMB and neoplasm.