Moreover, analysis of transcriptional expression profiles indicated that 11 and 9 KIF genes were upregulated in HR+/HER2– BC relative to normal control samples (log2 fold change [log2FC] > 0.58 corresponds to FC > 1.5-fold and P < 0.05) in the FUSCC and TCGA data sets, respectively (Figure 1B). This evidence concerns the gene ERBB2 and breast cancer.