The higher levels of LINC00519 in lung squamous cell carcinoma are associated with a worse outlook for patients, and research has also shown that LINC00519 may speed up the progression of the disease by interacting with miR-450b-5p and miR-515-5p, and by regulating a protein called YAP1 [34]. This evidence concerns the gene YAP1 and squamous cell lung carcinoma.