The short and most studied PTXs include C-reactive protein (CRP) and serum amyloid P (SAP/PTX2), which are acute-phase proteins produced by the liver in response to interleukin-6 (IL-6); these proteins can increase dramatically during inflammation and have proven efficient as markers for infections, cardiovascular diseases (CVD), autoimmune disorders, and cancers [18,20,21]. Here, IL6 is linked to cancer.