PTX3 plasma levels may be a better biomarker of pulmonary arterial hypertension than B-type natriuretic peptide, especially in patients with connective tissue disease [36]; whereas in acute coronary syndrome, PTX3’s diagnostic sensitivity and specificity have been shown to be higher than those of troponin T and heart-type fatty acid binding protein [37]. The gene discussed is PTX3; the disease is pulmonary arterial hypertension.