Recently, many potential protein biomarkers have been reported in the literature for the diagnosis of AML, e.g., complement factor C7, complement factor H, HPT (Haptoglobin), ApoE (Apolipoprotein E), plasminogen and ApoA1 (Apolipoprotein A1), via proteomics techniques [13,32,33,34]. The gene discussed is APOE; the disease is acute myeloid leukemia.