In the present study, NGS identified EGFR variants in 11.1% of non-squamous NSCLC samples, while the most common EGFR alterations were exon 19 deletions (49.4%) and exon 21 p.L8585R (26.4%), followed by exon 20 insertions (9.9%), exon 18 p.G719X (7.7%), exon 21 p.L861Q (4.4%) and exon 20 p.T790M (2.2%). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.