VEGFA and chronic thromboembolic pulmonary hypertension: The angiogenesis in patients with CTEPH is driven by the vascular endothelial growth factor (VEGF), functioning via the nitric oxide–soluble guanylate cyclase–cyclic guanosine monophosphate (NO-sGC-cGMP) pathway [8,9], and leading to the dissolution of thrombi and neovascularization [3].