Specifically, sCD163, IFN-α2, IFN-γ, IL-2, IL-10, IL-12p40, and MMP-1 levels were significantly lower in the LTI-2355-treated cultures of IPF myeloid cells compared with the control untreated IPF myeloid cells (Figure 4D). This evidence concerns the gene MMP1 and idiopathic pulmonary fibrosis.