In the serum, a decrease in the median concentration of Ela (252.00 [IQR: 188.75–445.00] pg/mL vs. 979.16 [IQR: 841.66–1425.00] pg/mL) and a decrease in the median concentration of AP-17 (47.16 [IQR: 31.60–67.50] pg/mL vs. 63.75 [IQR: 53.74–82.25] pg/mL], but an increase in the median level of the APJ receptor (7.65 [IQR: 5.43–12.27] ng/mL vs. 0.48 [IQR: 0.39–0.99] ng/mL), were found in the CAD patients in comparison to the healthy controls (p < 0.001 for all) (Figure 1, Figure 2 and Figure 3). The gene discussed is AP2S1; the disease is coronary artery disorder.