GBA1 and Parkinson disease: For our case and control stratified analyses, in addition to the GBA1 N370S signal, two PD-risk loci in SNCA became significantly associated with GCase activity in PD cases after applying multiple testing correction (rs356203, beta = 0.53, se = 0.17, p = 0.0015; rs356182, beta = 0.55, se = 0.17, p = 0.0017).