In streptozotocin-induced T1D in wild-type mice, Schistosoma mansoni infection inhibits the breakdown of pancreatic islets and hyperglycemia through increased Arg-1 and Ym1 expression rather than through processes that rely on Treg, IL-4, IL-13, and IL-10 [29]. Here, ARG1 is linked to type 1 diabetes mellitus.