Another case involved a 52-year-old non-smoking female initially diagnosed with an ethmoid inverted papilloma, with multiple recurrences as non-keratinizing SCC in the nasal cavity and maxillary sinus, ultimately manifesting as an obstructing tracheal mass that proven to be positive for DEK::AFF2 fusion 24 years later [6]. The gene discussed is AFF2; the disease is inverted papilloma.