A Th2-biased cytokine storm with more than 40-fold elevated circulating levels of interleukin-1Ra (IL-1Ra), IL-5, IL-6 and IL-10 was recently published in a systemic mastocytosis patient during prolonged MCA with no identified pathogen and with no clinical symptoms of an acute infection except elevated temperature [15]. The gene discussed is IL6; the disease is mastocytosis.