TGFB1 and metabolic dysfunction-associated steatohepatitis: Additionally, Tyr lowers the expression of prooxidant enzyme NOX1 [187] as well as the mRNA expressions of transforming growth factor β1 (TGF-β1) and IL-6, reducing inflammation associated with non-alcoholic steatohepatitis (NASH) and showing protective effects against liver immune infiltration [188].