BMP2 and pulpitis: Furthermore, peptides derived from BMP-2, such as the OP peptide BMP-2 residues 32-48 and 73-92, have been shown to enhance the MSC levels in RUNX2 and related alkaline phosphatase (ALP) proteins, indicating a role for BMP-2-derived peptides in promoting osteogenic differentiation.5-7Consequently, small molecules may represent a promising therapeutic approach for the prevention of pulpitis.