IL6 and Insulin resistance: Additionally, flavonoids, such as myricitrin, astragalin, quercitrin, quercetin [49], and puerarin [39], present anti-inflammation properties via suppressing some inflammatory cytokines involved in the inflammatory response through the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathways, such as TNF-α, IL-6, and IL-1β, whose release can impede insulin signaling, causing impaired glucose metabolism and insulin resistance [133].