These subgroups include AChR antibody‐positive generalized, ocular or thymoma‐associated myasthenia gravis, MuSK (muscle‐specific tyrosine kinase) and LRP4 (low density lipoprotein receptor‐related protein 4) antibody‐positive myasthenia gravis, and seronegative myasthenia gravis. The gene discussed is LRP4; the disease is myasthenia gravis.