LPA and coronary artery disorder: Less is known about the genetic pathogenesis of Lp(a) in East Asian populations, but previous studies, involving a few hundred participants, reported that the rs10455872 and rs3798220 LPA variants did not predict Lp(a) levels in East Asian individuals.21,22 In a GWAS study of Lp(a) levels in 1403 Chinese adults with CHD, Liu et al22 identified 4 GWAS-significant single nucleotide polymorphisms (SNPs) that were independently associated with Lp(a) and together explained 16% of variance in Lp(a) levels.