HECTD3 and Chronic pain: Among the 42 new chronic pain loci that harbor protein-coding variants (Supplementary Tables 4), five genes (HECTD3 (chr1.p34.3), CCDC17 (chr1.p34.3), DNM1 (chr9.q33.1), PCDHA1 (chr5.q31.5), and WDR90 (chr16.p13.3)) showed evidence of colocalization in more than one brain tissue.