Among the 42 new chronic pain loci that harbor protein-coding variants (Supplementary Tables 4), five genes (HECTD3 (chr1.p34.3), CCDC17 (chr1.p34.3), DNM1 (chr9.q33.1), PCDHA1 (chr5.q31.5), and WDR90 (chr16.p13.3)) showed evidence of colocalization in more than one brain tissue. Here, WDR90 is linked to Chronic pain.