Furthermore, four miRNAs (miR-1-3p/-21-3p/-93-5p/-155-5p) demonstrated similar trends in their expression in both GPA patient subgroups [GPA(+/+) and GPA(+/-)], compared to the control group, suggesting these miRNAs might be implicated in the pathogenesis of GPA. The gene discussed is GYPA; the disease is granulomatosis with polyangiitis.