Another study demonstrated that in a glioma mouse model receiving radiotherapy and chemotherapy, administration of NT-I7 (a long-acting IL-7) resulted in an increase in T lymphocytes across lymph nodes, thymus, and spleen, enhanced production of IFN-γ, and a reduction in intratumoral Tregs, which correlated positively with survival rates (195). The gene discussed is IFNG; the disease is glioma.