Compared to healthy Gingiva controls, OSCC tumor resection specimens without (N0) and with (N+) lymph node metastases showed a significantly increased infiltration of IL-23R expressing cells (mean 5 cells/mm2 vs. 127 cells/mm2 and 192 cells/mm2; p ≤ 0.016) (Table 1, Figure 5a). This evidence concerns the gene IL23R and neoplasm.