IFNAR2 and central nervous system cancer: We performed single-cell transcriptomic analysis on the orthotopic glioma mouse model (GSE246154) from the GEO database using R. The results indicated that the Ifnar2 gene was enriched in T cells (Supplementary Figures S4G, H), while the CD68 and CD33 genes were less enriched in macrophages (Supplementary Figure S5).