Prediction of RA using bootstrapping of a logistic regression model combining Prevotella, Peptoniphilus, EGF, the interaction between sCD40L and diet, menopausal status and clinic resulted in a mean AUC of 0.97 comparing 34 RA to a subset of 13 controls and 0.93 compared all 35 RA to the remaining 22 controls (95% CI [0.90, 1] and CI [86, 99], respectively) (Fig. S3C–F). The gene discussed is EGF; the disease is rheumatoid arthritis.