IL4 and infection: Among the polymorphisms associated in one cohort which were tested in different cohorts but where the association was not replicated, we have IL18 rs2043055 with CCC [81, 82], IFNG rs2430561 and infection [66, 69], IL4 −590 and infection [72, 73], TGFB1 −509 rs1800469 and infection [66, 68].