Haruki et al. (2020) explored whether the expression of markers of autophagy by CRC cells could be associated with tumour content of Fn. The study assessed the expression of BECN1 (beclin 1), MAP1LC3 (LC3), and SQSTM1 (p62) in tumour cells and their association with the amount of Fn, adjusted for potential molecular confounders (i.e. MSI, CIMP, and BRAF mutations). Here, FN1 is linked to neoplasm.