Recently, new findings revealed that Fn bacterial ferritins that protect DNA from oxidative stress (Fn- DNA hunger/stationary phase protective proteins [Dps]) is a novel multifunctional Fn virulence factor that lyses and disrupts erythrocytes, enhances intracellular survival of Fn in macrophages, and promotes the migration of CRC cells via the CCL2/CCL7-induced EMT and CRC metastasis. Here, PDSS1 is linked to colorectal carcinoma.