Haruki et al. (2020) explored whether the expression of markers of autophagy by CRC cells could be associated with tumour content of Fn. The study assessed the expression of BECN1 (beclin 1), MAP1LC3 (LC3), and SQSTM1 (p62) in tumour cells and their association with the amount of Fn, adjusted for potential molecular confounders (i.e. MSI, CIMP, and BRAF mutations). The gene discussed is SQSTM1; the disease is colorectal carcinoma.