Besides the above-mentioned association with right-sided MSI CRC, in a model adjusted for patient age, sex, CRC location, and BMI, patients with high faecal Fn abundance had a 3-fold increased likelihood of being diagnosed with rectal compared with colon tumours, and 5-fold increased risk compared with right-sided CRC (Eisele et al., 2021). The gene discussed is FN1; the disease is colorectal carcinoma.