In any case, patients with high loads of Fn in their tumours had an increased risk of disease-specific mortality, irrespective of MS-status (HR=1.27 for non-MSI-high CRCs, HR=2.23 for MSI-high CRCs at multivariable analysis) (Hamada et al., 2018) (Table 6). This evidence concerns the gene FN1 and neoplasm.