APOB and metabolic syndrome: [275] found beneficial lipid‐lowering effects of H2 in animal studies, and thus they included 20 patients with potential metabolic syndrome to investigate the ameliorative effects of H2‐enriched water in humans, showing that supplementation with H2‐enriched water appeared to reduce serum low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (apoB) levels, and to improve the function of dyslipidemia‐impaired high‐density lipoprotein cholesterol, reducing oxidative stress.