GP73-positive HCC patients tended to exhibit lower immunohistochemical scores for CD4+ T cells and CD8+ T cells, higher immunohistochemical score for Foxp3+ Treg cells, higher immunohistochemical score for nuclear Ki67, and lower immunohistochemical score for IFN-γ compared with GP73-negative patients (regardless of analysis in cancerous or adjacent tissues). The gene discussed is FOXP3; the disease is hepatocellular carcinoma.