NUMB and endometrial cancer: A retrospective cohort study was performed on 41 patients with endometrial cancer who were divided into three groups according to the expression level of NUMB protein using immunohistochemistry: NUMB 1 (mild), NUMB 2 (moderate), and NUMB 3 (significant). Statistical analyses, including ANOVA, Kruskal-Wallis test, chi-squared test, Kaplan-Meier survival analysis, Cox proportional hazards model, and regression analyses, were used to assess the relationship between NUMB expression and survival as well as various clinicopathological parameters.