High expression of lncR-AC026356.1 positively correlates with T cells depletion that maintains NSCLC cancer stem cell (CSCs) properties through activation of the Wnt/β-catenin signaling pathway, with the result of inhibiting NSCLC cell sensitivity to anti-PD-1/PD-L1 inhibitors [140,141]. Here, CD274 is linked to non-small cell lung carcinoma.