Compared with those in control tissue, lymphoma showed significant increases of in LC3B (LC3BI represents early autophagy, while LC3BII represents autophagic flux), autophagy related 14 (Atg14) and Beclin-1 levels, and a decrease in p62 (sequestosome 1) levels (Fig. 1B). This evidence concerns the gene SQSTM1 and lymphoma.